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semaglutide and mcas Not all GLP 1s work the same way for MCAS. Most patients do better on Tirzepatide, the dual incretin with both GLP 1 and GIP receptor agonists. But some mast cells Semaglutide vs. Ozempic: What's the difference? how many units is 20 mg of tirzepatide How to Convert Tirzepatide Units to Milligrams for What Is Zepbound (tirzepatide)? Uses, Side Effects, Dosage GoodRx Will semaglutide show on a drug test? Bmi Doctors Tirzepatide for obesity and diabetes prevention progression to T2D in prediabetes#SURMOUNT1 trial Up to 20% weight loss over 3 years with tirzepatide, reducing T2D onset by 93% vs. placebo. After
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.7 ★★★★★
Based on 1363 reviews
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Product Reviews
★★★★★ 3
Way too narrow
Size: 9.5 Wide, Color: Burgundy Polished Full Grain
I ordered a wide in this shoe, but it was still way too narrow. I had to return them. Otherwise, it looked like a nice quality shoe.
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Reviewed in the United States on February 12, 2026
★★★★★ 5
I usually wear 11.5's, but I buy 1/2 size smaller to accommodate for stretch. Leather relaxes.
Size: 11, Color: Burgundy Polished Full Grain
5 STARS: These shoes are awesome. I keep coming back for more. I have major foot problems, have tried all kinds of shoes, orthotics, and inserts... but believe it or not, these shoes work better than any of that stuff. I wear them daily. I buy lots of them, for home, for church, and I'm getting my first pair of J&M boots today, for winters in Indiana... Brrrr
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Reviewed in the United States on December 18, 2025
★★★★★ 5
Great price great shoe
Size: 12, Color: Burgundy Polished Full Grain
Excellent shoe. Tried the Sebago penny loafer and the sizing was ridiculous. These J and M are sized perfectly. I’ve had them before and they wear like iron. Very comfortable right out of the box.
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Reviewed in the United States on May 23, 2026
★★★★★ 5
One of the best shoes
Size: 9.5, Color: Black Polished Full Grain
Outstanding. Fashionable, most comfortable and good construction. No sines of use after quite some time. Highly recommended.
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Reviewed in the United States on March 21, 2026
★★★★★ 4
Quality shoe but with a slight squeak.
Size: 10 Wide, Color: Burgundy Polished Full Grain
Nice shoes with the classic Penny Loafer design. Fit was better than another brand I tried. Only reason not 5 starts is disappointment due to a slight squeak at times when walking.
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Reviewed in the United States on August 11, 2025
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